REVENUE MEMORANDUM CIRCULAR NO. 51-2022 issued on April 21, 2022 publishes the letter from Food and Drug Administration OIC-Director General, Dr. Oscar G. Gutierrez Jr. endorsing updates to the List of VAT-Exempt Medicines under Republic Act No. 11534 (CREATE Act). The list includes certain medicines for COVID-19 treatment and hypertension, and corrects a medicine for cancer.